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Figure 10. Infarction in a 12-year-old boy with homozygous sickle cell disease, left tibial pain, and a low-grade fever. Medial (left) and lateral (right) views of the left (L) tibia from late static phase 99mTc MDP scintigraphy show an area of decreased tracer uptake within the proximal shaft (arrowheads), a finding suggestive of infarction. A bone aspirate culture was negative, and the patient underwent conservative treatment. (Images courtesy of Muriel Buxton-Thomas, Nuclear Medicine Department, Kings College Hospital NHS Trust.)