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Figure 12a. Ganglion of the Guyon canal in a 38-year-old man. (a) Axial T2-weighted MR image of the wrist shows a lobulated homogeneous mass (arrowhead) with fluid signal intensity volar to the hook of the hamate. (b) Axial T1-weighted fat-suppressed image of the wrist after intravenous administration of a gadolinium chelate shows only peripheral enhancement of the mass (arrowhead), a feature typical of a ganglion. Nearly 2% of patients referred to the Orthopaedic Oncology Clinic arrived with MR images that showed characteristic features of a juxta-articular cyst or ganglion that was misinterpreted as a potential malignancy. The signal intensity and enhancement patterns usually allow a confident diagnosis.