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Figure 1d. Right frontal anaplastic oligoastrocytoma (World Health Organization [WHO] grade III) in a 39-year-old man. The diagnosis was proved at biopsy. (a) Axial postcontrast T1-weighted MR image demonstrates a nonenhancing right frontal mass. (b) On an axial relative cerebral blood volume (rCBV) map, there is elevated rTBV compared with contralateral normal brain tissue, especially at the posterior periphery of the lesion. (c) Intermediate-echo MR spectrum shows a decrease in the NAA (at 2.02 ppm) and creatine (Cr) (at 3.0 ppm) peaks and elevation of the choline (Cho) peak (at 3.2 ppm). (d, e) These observations are further illustrated with spectroscopic color maps of the NAA/creatine (d) and choline/creatine (e) ratios.