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Figure 5a. Areas of activation for the verbal fluencyverb generation paradigm. The subject was a left-handed 34-year-old man with a left hemispheric temporal lobe lesion who presented with speech disorders and seizures. T1-weighted MR images show a very large lesion in the left temporal lobe (arrows in a), an area of superimposed activation in the left inferior frontal gyrus (classic Broca area) (arrows in b), and areas of equal activation bilaterally in the medial temporal gyri (classic Wernicke area) (arrows in c). Conclusions: left hemispheric dominance for language; classic Wernicke area activation adjacent to lesion.