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Figure 2b. Areas of activation for the semantic paradigm as determined with a fixed-effects group analysis of six right-handed volunteers (T > 5, cluster >10 voxels). (a) Silent gap acquisition. On high-resolution T1-weighted MR images, superimposed activation is seen only in the posterior language areas, predominantly in the left hemisphere. (b) Continuous acquisition. High-resolution T1-weighted MR images show much more widespread (superimposed) activation, with additional activation in the frontal language areas. Although activation is still predominantly left hemispheric, a substantial amount is also seen in the right hemisphere. Presumably, since the words are more difficult to hear with continuous acquisition, the subject will need to concentrate more on the words themselves, not just on the meaning of the words (ie, additional phonologic processing areas of the brain are recruited).
