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Figure 2e. Malignant features. (a) Contrast-enhanced T1-weighted fat-saturated GRE (20/4.5; flip angle, 30°) image shows two masses in the left breast of a 44-year-old woman, one with thin rimlike enhancement at the 4-oclock position (arrowhead) and the other with heterogeneous enhancement and enhanced internal septa at the 2-oclock position (arrow). (b) T2-weighted (4000/90) fat-saturated image (same patient as in a) shows low signal intensity in the portions of the masses that appeared enhanced in a. A central region of necrosis in the mass at the 4-oclock position shows increased internal T2-weighted signal intensity. The masses proved to be poorly differentiated ductal carcinoma with necrosis and signet ring cell features. (c) Contrast-enhanced T1-weighted GRE (20/4.5; flip angle, 30°) subtraction image from a 42-year-old woman shows a spiculated margin in an infiltrating carcinoma with ductal and lobular features. (d) Contrast-enhanced T1-weighted fat-saturated GRE (20/4.5; flip angle, 30°) image from a 52-year-old woman shows a retroareolar mass (arrow) with an irregular margin and heterogeneous enhancement. The results of histologic analysis indicated infiltrating ductal carcinoma. (e) T2-weighted (4000/90) fat-saturated image (same patient as in d) shows the mass (arrow) with low signal intensity. Note the focal skin thickening and nipple retraction.