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Figure 5. High-power photomicrograph (original magnification, x400; HPS stain) shows a metastatic nodule (arrow) with moderate nuclear pleomorphism, coarse chromatin, and, in some cells, a prominent acidophilic nucleolus. Most cells contain a large amount of cytoplasm, which is finely granular, acidophilic, and, occasionally, vacuolated. Numerous focal mitoses (not shown) were also seen.
