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Figure 16. Probable brown fat uptake on the nonirradiated side in a 37-year-old man with non-Hodgkin lymphoma who had undergone chemotherapy and radiation therapy to the left side of the neck. Coronal PET scan shows increased FDG uptake in the right supraclavicular region (arrow); however, no abnormality was seen at CT. Physiologic uptake is seen in the vocal cords (arrowhead), myocardium, liver, and digestive tract. The patient remains disease free. Brown fat (supraclavicular area fat) is adipose tissue whose only function is to generate heat. It usually demonstrates the symmetric uptake pattern shown here and is more common in women and during the winter (35,36).
