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Figure 12b. Increased bone marrow uptake due to G-CSF therapy and lymphomatous infiltration in a 45-year-old man with Hodgkin disease. (a) Baseline sagittal PET scan shows focal FDG uptake in the lower thoracic spine (arrowhead). (b) Corresponding sagittal T1-weighted MR image shows a marrow-replacing lesion in the lower thoracic spine (arrowhead). (c) On a sagittal PET scan obtained after completion of chemotherapy, the previously involved spine shows decreased activity (arrowhead), whereas the normal bone marrow shows increased activity due to G-CSF therapy. (d) Corresponding sagittal T1-weighted MR image shows fatty infiltration of the previously involved lower thoracic spine (arrowhead).