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Figure 13a.  Mucinous cystadenoma with stromal hyperplasia in a 65-year-old woman. (a, b) Coronal T2-weighted (a) and contrast-enhanced fat-saturated T1-weighted (b) MR images show a multilocular cystic mass (arrows) containing fluid with varying signal intensities on the right cranial side of the enlarged uterus (arrowheads in a). The patient presented with atypical genital bleeding, and the endometrium has higher signal intensity than that normally seen in postmenopausal women on the T2-weighted image (a). This appearance is similar to that of a GCT with a macrofollicular pattern. (c) Photomicrograph (original magnification, x10; H-E stain) reveals that the tumor is composed of cysts, the epithelial lining of which is mucin-filled columnar cells (arrows). The histopathologic diagnosis was mucinous cystadenoma. Conversely, this tumor has relatively rich stroma, which can contain testosterone-aromatizing enzymes. The increased serum estradiol level returned to normal after surgery. (Reprinted, with permission, from reference 36.)







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