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Figure 14c. Splenic hamartoma. (a) Photomicrograph (original magnification, x10; H-E stain) shows disorganized sinuses and splenic red pulp elements (*) compared with the organized sinuses in the normal spleen (upper portion of the image). (b) Photomicrograph (original magnification, x40; H-E stain) shows an irregular, disorganized splenic sinus containing a megakaryocyte and nucleated red cells. (c) Photomicrograph (original magnification, x40; CD8 stain) shows CD8 positivity of the sinus lining cells (brown staining).
