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Figure 1a.  Neck deformity and connective-tissue nevus. Photographs of the neck (a) and right foot (b) of an 11-year-old patient show severe deformity of the chest and neck, caused by vertebral anomalies; disproportionate growth of the forefoot (the fifth toe has been amputated because of macrodactyly; see Fig 4); and plantar cerebriform connective-tissue nevus. Vertebral anomalies and connective-tissue nevi are characteristic features of Proteus syndrome.







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