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Figure 19b.   Hamartoma in an asymptomatic man. (a) Chest CT scan shows a heterogeneous, sharply marginated lesion with small focal areas of calcification and fat. These findings are typical features of hamartoma. (b) Photograph of a resected specimen demonstrates a yellowish, glistening, lobular cut surface, a finding that is consistent with fat. (c) Photomicrograph (original magnification, x100; hematoxylin-eosin stain) helps confirm the presence of adipose tissue (arrow) and shows epithelial tissue containing an island of basophilic cartilage (arrowhead). This mixture of epithelial and mesenchymal tissue is diagnostic for hamartoma. (Fig 19 courtesy of M. Rosado de Christenson, Col, USAF, MC, Armed Forces Institute of Pathology, Washington, DC.)