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Figure 29a. Large cell lymphoma in the same patient as in Figure 16, who tested positive for HIV infection. Multiple sites of involvement included the kidneys and heart. Contrast-enhanced helical CT scans show soft-tissue masses in the perirenal space (a) and within the septum and myocardium of both ventricles (arrows in b). The patient died of acquired immunodeficiency syndrome. Histologic cardiac involvement is common in acquired immunodeficiency syndrome, but bulky lesions as seen in this case are relatively rare.