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Figure 11axy. FDG uptake in bone marrow. (a) Axial FDG PET images (shown from superior [top left] to inferior [bottom center]) show normal FDG activity in the marrow of the vertebral bodies (arrows). Sagittal FDG PET image (bottom right) clearly shows the modest FDG uptake at each vertebral body. (b) Axial FDG PET images (shown from superior [top left] to inferior [bottom center]) of a patient with lung cancer show metastases to the marrow spaces of the vertebral bodies (arrowheads) and left pedicle (arrow). Sagittal FDG PET image (bottom right) shows the irregular intensity and nonuniform distribution of the FDG uptake in the metastases. Metastases are also present in the left rib and sternum.