HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Zicherman, J. M. Articles by Epstein, R. Search for Related Content PubMed PubMed Citation Articles by Zicherman, J. M. Articles by Epstein, R. Related Collections Genitourinary Radiology

Best Cases from the AFIP

Primary Diffuse Large B-Cell Lymphoma of the Epididymis and Testis¹

¹ From the Departments of Radiology (J.M.Z., C.G., R.E.) and Pathology (D.W.), University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, Medical Education Building, Room 404, New Brunswick, NJ 08903. Received March 15, 2004; revision requested April 6 and received May 18; accepted May 18. All authors have no financial relationships to disclose. Address correspondence to J.M.Z. (e-mail: zicherja@yahoo.com).

View larger version (119K): [in a new window]   Figure 1a.  (a) Axial contrast-enhanced CT scan shows a soft-tissue mass within the right hemiscrotum (arrow). (b) Doppler US image shows a 2.4 x 2.8-cm hypoechoic hypervascular mass occupying the right epididymis (white *) and infiltrating the superior pole of the adjacent testis (black *).

View larger version (211K): [in a new window]   Figure 1b.  (a) Axial contrast-enhanced CT scan shows a soft-tissue mass within the right hemiscrotum (arrow). (b) Doppler US image shows a 2.4 x 2.8-cm hypoechoic hypervascular mass occupying the right epididymis (white *) and infiltrating the superior pole of the adjacent testis (black *).

View larger version (126K): [in a new window]   Figure 2a.  (a) Sagittal fast spin-echo T2-weighted MR image (repetition time msec/echo time msec = 3,116/112) demonstrates a hypointense mass within the right epididymis (*). Note the margin between the infiltrating epididymal mass and the superior pole of the right testis (arrows). (b) Coronal MR image (3,116/112) demonstrates the mass occupying the epididymis (*) and invading the superior pole of the right testis (arrow). (c) Photograph of the resected specimen obtained at right orchiectomy demonstrates a tan-white indurated mass replacing the right epididymis (*). The mass is irregular in shape and focally invades the superior pole of the testis (arrow).

View larger version (114K): [in a new window]   Figure 2b.  (a) Sagittal fast spin-echo T2-weighted MR image (repetition time msec/echo time msec = 3,116/112) demonstrates a hypointense mass within the right epididymis (*). Note the margin between the infiltrating epididymal mass and the superior pole of the right testis (arrows). (b) Coronal MR image (3,116/112) demonstrates the mass occupying the epididymis (*) and invading the superior pole of the right testis (arrow). (c) Photograph of the resected specimen obtained at right orchiectomy demonstrates a tan-white indurated mass replacing the right epididymis (*). The mass is irregular in shape and focally invades the superior pole of the testis (arrow).

View larger version (76K): [in a new window]   Figure 2c.  (a) Sagittal fast spin-echo T2-weighted MR image (repetition time msec/echo time msec = 3,116/112) demonstrates a hypointense mass within the right epididymis (*). Note the margin between the infiltrating epididymal mass and the superior pole of the right testis (arrows). (b) Coronal MR image (3,116/112) demonstrates the mass occupying the epididymis (*) and invading the superior pole of the right testis (arrow). (c) Photograph of the resected specimen obtained at right orchiectomy demonstrates a tan-white indurated mass replacing the right epididymis (*). The mass is irregular in shape and focally invades the superior pole of the testis (arrow).

View larger version (193K): [in a new window]   Figure 3.  Photomicrograph (original magnification, x40; hematoxylin-eosin [H-E] stain) demonstrates sarcomatoid lymphoma cells surrounding a sclerosed and predominantly effaced seminiferous tubule (*). The lymphoma cells are spindled or twisted, with an irregular nuclear contour (arrow).

View larger version (198K): [in a new window]   Figure 4.  Photomicrograph (original magnification, x20; H-E stain) shows a section of the epididymis surrounded by a diffuse lymphomatous infiltrate. The lymphoma cells are sarcomatoid like those shown in Figure 3.

View larger version (184K): [in a new window]   Figure 5.  Photomicrograph (original magnification, x10; H-E stain) demonstrates the interface between the uninvolved testis (top) and the portion of the testis involved by lymphoma (bottom).

View larger version (190K): [in a new window]   Figure 6.  Photomicrograph (original magnification, x40; H-E stain) shows diffuse large cells, most of which have large vesicular nuclei with nucleoli that tend to cling to the nuclear envelope (arrow). A few larger, more anaplastic forms with lobate nuclei are also present.