Imaging of Musculoskeletal Fibromatosis1
Mark R. Robbin, MD,
Mark D. Murphey, MD,
H. Thomas Temple, MD,
Mark J. Kransdorf, MD and
James J. Choi, MD
1 From the Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, 10900 Euclid Ave, Cleveland, OH 44106 (M.R.R.); the Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC (M.D.M., J.J.C.); the Departments of Radiology and Nuclear Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md (M.D.M.); the Department of Radiology, University of Maryland School of Medicine, Baltimore (M.D.M.); the Department of Orthopedic Surgery, University of Miami School of Medicine, Miami, Fla (H.T.T.); and the Department of Radiology, Mayo Clinic, Jacksonville, Fla (M.J.K.). Recipient of a Certificate of Merit award for a scientific exhibit at the 1997 RSNA scientific assembly. Received June 5, 2000; revision requested July 14; final revision received February 15, 2001; accepted February 15. Address correspondence to M.R.R. (e-mail: robbin@uhrad.com).
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Figure 1a. Histopathologic features of fibromatosis. Photographs of gross specimens show examples of well-defined margins in fibromatosis (a) as well as a lesion with infiltrative margins (arrows in b).
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Figure 1b. Histopathologic features of fibromatosis. Photographs of gross specimens show examples of well-defined margins in fibromatosis (a) as well as a lesion with infiltrative margins (arrows in b).
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Figure 2a. Histopathologic features of fibromatosis. (a) Photomicrograph (original magnification, x200; hematoxylin-eosin stain) shows a lesion that is predominantly cellular with relatively less fibrosis. (b) Photomicrograph (original magnification, x250; hematoxylin-eosin stain) shows a lesion that is predominantly fibrotic with less cellularity.
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Figure 2b. Histopathologic features of fibromatosis. (a) Photomicrograph (original magnification, x200; hematoxylin-eosin stain) shows a lesion that is predominantly cellular with relatively less fibrosis. (b) Photomicrograph (original magnification, x250; hematoxylin-eosin stain) shows a lesion that is predominantly fibrotic with less cellularity.
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Figure 3a. Palmar fibromatosis. (a) Clinical photograph shows multiple subcutaneous cords and nodules (arrowheads) at the bases of the second through fifth digits, which resulted in flexion contractures. (b, c) Axial (b) and sagittal (c) T1-weighted magnetic resonance (MR) images (repetition time msec/echo time msec = 633/20) obtained in another patient show the fibromatosis as a low-signal-intensity band (arrowheads) superficial to and paralleling the flexor tendon (arrow) of the fifth digit.
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Figure 3b. Palmar fibromatosis. (a) Clinical photograph shows multiple subcutaneous cords and nodules (arrowheads) at the bases of the second through fifth digits, which resulted in flexion contractures. (b, c) Axial (b) and sagittal (c) T1-weighted magnetic resonance (MR) images (repetition time msec/echo time msec = 633/20) obtained in another patient show the fibromatosis as a low-signal-intensity band (arrowheads) superficial to and paralleling the flexor tendon (arrow) of the fifth digit.
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Figure 3c. Palmar fibromatosis. (a) Clinical photograph shows multiple subcutaneous cords and nodules (arrowheads) at the bases of the second through fifth digits, which resulted in flexion contractures. (b, c) Axial (b) and sagittal (c) T1-weighted magnetic resonance (MR) images (repetition time msec/echo time msec = 633/20) obtained in another patient show the fibromatosis as a low-signal-intensity band (arrowheads) superficial to and paralleling the flexor tendon (arrow) of the fifth digit.
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Figure 4a. Plantar fibromatosis in a 65-year-old woman. (a) Clinical photograph shows a nodular soft-tissue mass along the medial plantar surface (arrows). (b, c) Sagittal T1-weighted (500/20) (b) and T2-weighted (2,000/80) (c) MR images show the mass (arrowheads). The high signal intensity on the T2-weighted image (c) corresponded to a more cellular lesion with less collagen than many fibromatoses (cf Fig 2a).
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Figure 4b. Plantar fibromatosis in a 65-year-old woman. (a) Clinical photograph shows a nodular soft-tissue mass along the medial plantar surface (arrows). (b, c) Sagittal T1-weighted (500/20) (b) and T2-weighted (2,000/80) (c) MR images show the mass (arrowheads). The high signal intensity on the T2-weighted image (c) corresponded to a more cellular lesion with less collagen than many fibromatoses (cf Fig 2a).
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Figure 4c. Plantar fibromatosis in a 65-year-old woman. (a) Clinical photograph shows a nodular soft-tissue mass along the medial plantar surface (arrows). (b, c) Sagittal T1-weighted (500/20) (b) and T2-weighted (2,000/80) (c) MR images show the mass (arrowheads). The high signal intensity on the T2-weighted image (c) corresponded to a more cellular lesion with less collagen than many fibromatoses (cf Fig 2a).
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Figure 5. Juvenile aponeurotic fibroma in a 12-year-old boy. Radiographs of the long finger show a calcified soft-tissue mass (arrow) with mild extrinsic erosion of the middle phalanx (arrowhead).
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Figure 6. Infantile digital fibromatosis in a 4-year-old girl. Radiograph shows a soft-tissue mass (arrowhead) involving the fifth finger without bone involvement.
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Figure 7a. Infantile myofibromatosis in a 5-month-old girl. (a, b) Clinical photograph (a) and anteroposterior skull radiograph (b) show a large, exophytic soft-tissue mass (arrow) extending from the left side of the neck. (c) Lower-extremity radiograph shows multiple geographic, symmetric, lytic lesions in the metaphyses of the long bones (arrowheads). Lytic lesions were also seen in the ribs, right scapula, and clavicles.
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Figure 7b. Infantile myofibromatosis in a 5-month-old girl. (a, b) Clinical photograph (a) and anteroposterior skull radiograph (b) show a large, exophytic soft-tissue mass (arrow) extending from the left side of the neck. (c) Lower-extremity radiograph shows multiple geographic, symmetric, lytic lesions in the metaphyses of the long bones (arrowheads). Lytic lesions were also seen in the ribs, right scapula, and clavicles.
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Figure 7c. Infantile myofibromatosis in a 5-month-old girl. (a, b) Clinical photograph (a) and anteroposterior skull radiograph (b) show a large, exophytic soft-tissue mass (arrow) extending from the left side of the neck. (c) Lower-extremity radiograph shows multiple geographic, symmetric, lytic lesions in the metaphyses of the long bones (arrowheads). Lytic lesions were also seen in the ribs, right scapula, and clavicles.
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Figure 8a. Fibromatosis colli in a 6-week-old girl. (a) Transverse US scan shows a diffusely enlarged right sternocleidomastoid muscle (arrowheads) relative to the normal left sternocleidomastoid muscle (not shown). (b, c) Coronal T1-weighted (800/15) (b) and T2-weighted (2,000/90) (c) MR images show an enlarged right sternocleidomastoid muscle (arrows in b). A poorly defined mass with mild increased signal intensity (arrowheads) is seen on the long repetition time image (c).
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Figure 8b. Fibromatosis colli in a 6-week-old girl. (a) Transverse US scan shows a diffusely enlarged right sternocleidomastoid muscle (arrowheads) relative to the normal left sternocleidomastoid muscle (not shown). (b, c) Coronal T1-weighted (800/15) (b) and T2-weighted (2,000/90) (c) MR images show an enlarged right sternocleidomastoid muscle (arrows in b). A poorly defined mass with mild increased signal intensity (arrowheads) is seen on the long repetition time image (c).
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Figure 8c. Fibromatosis colli in a 6-week-old girl. (a) Transverse US scan shows a diffusely enlarged right sternocleidomastoid muscle (arrowheads) relative to the normal left sternocleidomastoid muscle (not shown). (b, c) Coronal T1-weighted (800/15) (b) and T2-weighted (2,000/90) (c) MR images show an enlarged right sternocleidomastoid muscle (arrows in b). A poorly defined mass with mild increased signal intensity (arrowheads) is seen on the long repetition time image (c).
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Figure 9a. Desmoid tumor of the abdominal wall in a 29-year-old woman taking birth control pills. (a) Contrast material-enhanced CT scan shows an intensely enhanced mass arising from the lateral abdominal wall (arrowheads). (b) Axial T1-weighted MR image (544/18) shows that the mass (arrows) has intermediate signal intensity. (c) Axial T2-weighted MR image (1,800/180) shows that the mass (arrows) has heterogeneous high signal intensity. (d) Photograph of the gross surgical specimen shows the well-defined mass (arrows).
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Figure 9b. Desmoid tumor of the abdominal wall in a 29-year-old woman taking birth control pills. (a) Contrast material-enhanced CT scan shows an intensely enhanced mass arising from the lateral abdominal wall (arrowheads). (b) Axial T1-weighted MR image (544/18) shows that the mass (arrows) has intermediate signal intensity. (c) Axial T2-weighted MR image (1,800/180) shows that the mass (arrows) has heterogeneous high signal intensity. (d) Photograph of the gross surgical specimen shows the well-defined mass (arrows).
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Figure 9c. Desmoid tumor of the abdominal wall in a 29-year-old woman taking birth control pills. (a) Contrast material-enhanced CT scan shows an intensely enhanced mass arising from the lateral abdominal wall (arrowheads). (b) Axial T1-weighted MR image (544/18) shows that the mass (arrows) has intermediate signal intensity. (c) Axial T2-weighted MR image (1,800/180) shows that the mass (arrows) has heterogeneous high signal intensity. (d) Photograph of the gross surgical specimen shows the well-defined mass (arrows).
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Figure 9d. Desmoid tumor of the abdominal wall in a 29-year-old woman taking birth control pills. (a) Contrast material-enhanced CT scan shows an intensely enhanced mass arising from the lateral abdominal wall (arrowheads). (b) Axial T1-weighted MR image (544/18) shows that the mass (arrows) has intermediate signal intensity. (c) Axial T2-weighted MR image (1,800/180) shows that the mass (arrows) has heterogeneous high signal intensity. (d) Photograph of the gross surgical specimen shows the well-defined mass (arrows).
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Figure 10a. Extraabdominal desmoid tumor involving the paraspinal region in a 57-year-old man. (a) Sagittal T1-weighted MR image (550/20) shows a large paraspinal mass (arrows) with signal intensity similar to that of muscle. (b) Axial T2-weighted MR image (2,000/90) shows that the mass (black arrows) has heterogeneous high signal intensity with low-signal-intensity bands (arrowheads). The ill-defined infiltrative margins (white arrows) correspond to those of the gross specimen shown in Figure 1b.
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Figure 10b. Extraabdominal desmoid tumor involving the paraspinal region in a 57-year-old man. (a) Sagittal T1-weighted MR image (550/20) shows a large paraspinal mass (arrows) with signal intensity similar to that of muscle. (b) Axial T2-weighted MR image (2,000/90) shows that the mass (black arrows) has heterogeneous high signal intensity with low-signal-intensity bands (arrowheads). The ill-defined infiltrative margins (white arrows) correspond to those of the gross specimen shown in Figure 1b.
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Figure 11a. Extraabdominal desmoid tumor of the right shoulder in a 20-year-old woman. (a) Coronal T1-weighted MR image (400/15) shows a vague mass lateral to the humerus (arrowheads). (b) Axial fat-suppressed T1-weighted MR image (500/20) obtained after intravenous administration of gadolinium contrast material shows that the mass (large arrowheads) is intermuscular and invades the subcutaneous fat (arrow). The mass demonstrates marked enhancement and irregular infiltrative margins. (c) Axial T2-weighted MR image (2,500/80) shows that the mass has heterogeneous intermediate signal intensity (less than that of fat) with low-signal-intensity collagenized bands (arrows); these bands lack prominent enhancement on the postcontrast image (small arrowheads in b).
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Figure 11b. Extraabdominal desmoid tumor of the right shoulder in a 20-year-old woman. (a) Coronal T1-weighted MR image (400/15) shows a vague mass lateral to the humerus (arrowheads). (b) Axial fat-suppressed T1-weighted MR image (500/20) obtained after intravenous administration of gadolinium contrast material shows that the mass (large arrowheads) is intermuscular and invades the subcutaneous fat (arrow). The mass demonstrates marked enhancement and irregular infiltrative margins. (c) Axial T2-weighted MR image (2,500/80) shows that the mass has heterogeneous intermediate signal intensity (less than that of fat) with low-signal-intensity collagenized bands (arrows); these bands lack prominent enhancement on the postcontrast image (small arrowheads in b).
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Figure 11c. Extraabdominal desmoid tumor of the right shoulder in a 20-year-old woman. (a) Coronal T1-weighted MR image (400/15) shows a vague mass lateral to the humerus (arrowheads). (b) Axial fat-suppressed T1-weighted MR image (500/20) obtained after intravenous administration of gadolinium contrast material shows that the mass (large arrowheads) is intermuscular and invades the subcutaneous fat (arrow). The mass demonstrates marked enhancement and irregular infiltrative margins. (c) Axial T2-weighted MR image (2,500/80) shows that the mass has heterogeneous intermediate signal intensity (less than that of fat) with low-signal-intensity collagenized bands (arrows); these bands lack prominent enhancement on the postcontrast image (small arrowheads in b).
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Figure 12a. Aggressive infantile fibromatosis in a newborn. (a) CT scan of the thorax shows a large, posterior soft-tissue mass (arrowheads) invading the thoracic spine and posterior chest wall (arrows). (b, c) Axial T1-weighted (550/20) (b) and sagittal T2-weighted (2,000/90) (c) MR images show that the mass has heterogeneous intermediate signal intensity and low-signal-intensity bands (arrows) with both sequences. There is invasion of the spinal canal and posterior chest wall (arrowheads).
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Figure 12b. Aggressive infantile fibromatosis in a newborn. (a) CT scan of the thorax shows a large, posterior soft-tissue mass (arrowheads) invading the thoracic spine and posterior chest wall (arrows). (b, c) Axial T1-weighted (550/20) (b) and sagittal T2-weighted (2,000/90) (c) MR images show that the mass has heterogeneous intermediate signal intensity and low-signal-intensity bands (arrows) with both sequences. There is invasion of the spinal canal and posterior chest wall (arrowheads).
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Figure 12c. Aggressive infantile fibromatosis in a newborn. (a) CT scan of the thorax shows a large, posterior soft-tissue mass (arrowheads) invading the thoracic spine and posterior chest wall (arrows). (b, c) Axial T1-weighted (550/20) (b) and sagittal T2-weighted (2,000/90) (c) MR images show that the mass has heterogeneous intermediate signal intensity and low-signal-intensity bands (arrows) with both sequences. There is invasion of the spinal canal and posterior chest wall (arrowheads).
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Figure 13a. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13b. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13c. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13d. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13e. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13f. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 13g. Recurrent aggressive fibromatosis of the foot in a 17-year-old girl. (a) Radiograph of the foot shows a recurrent soft-tissue mass that causes extrinsic erosion of the first and second metatarsals. (b) Sagittal T1-weighted MR image (400/15) shows that the mass (arrows) is large, with extensive invasion of the deep plantar tissues. (c) Clinical photograph shows the mass along the medial aspect of the foot (arrow). Surgical resection was performed. (d, e) Sagittal T1-weighted (550/25) (d) and fat-saturated T2-weighted (5,000/80) (e) MR images obtained 2 years later show an aggressive recurrent soft-tissue mass (arrowheads). The lesion has heterogeneous high signal intensity on the T2-weighted image (e), which corresponds to increased cellularity. (f) Clinical photograph shows the mass and secondary ulceration of the skin (arrowheads) from secondary infection. Amputation was performed due to the extensive infiltrative nature of the lesion. (g) Photograph of the sagittally sectioned gross specimen shows that the lesion represents recurrent aggressive fibromatosis (arrowheads).
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Figure 14a. Recurrent extraabdominal desmoid tumor in a 19-year-old woman. (a, b) Sagittal T1-weighted (800/20) (a) and T2-weighted (2,000/100) (b) MR images show a heterogeneous intermuscular soft-tissue mass in the popliteal fossa (arrowheads). Bands of low signal intensity (white arrows in a, solid arrows in b) are prominent. Linear extension along fascial planes inferiorly (black arrows in a, open arrow in b) was not recognized at surgical resection. (c) Sagittal T1-weighted MR image (500/20) obtained 16 months after surgical resection shows a recurrent intermuscular soft-tissue mass (arrows) along the gastrocnemius muscle and soleus aponeurosis at the site of previously identified fascial extension. The mass has signal intensity characteristics similar to those of the original lesion, with bands of low signal intensity (arrowheads).
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Figure 14b. Recurrent extraabdominal desmoid tumor in a 19-year-old woman. (a, b) Sagittal T1-weighted (800/20) (a) and T2-weighted (2,000/100) (b) MR images show a heterogeneous intermuscular soft-tissue mass in the popliteal fossa (arrowheads). Bands of low signal intensity (white arrows in a, solid arrows in b) are prominent. Linear extension along fascial planes inferiorly (black arrows in a, open arrow in b) was not recognized at surgical resection. (c) Sagittal T1-weighted MR image (500/20) obtained 16 months after surgical resection shows a recurrent intermuscular soft-tissue mass (arrows) along the gastrocnemius muscle and soleus aponeurosis at the site of previously identified fascial extension. The mass has signal intensity characteristics similar to those of the original lesion, with bands of low signal intensity (arrowheads).
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Figure 14c. Recurrent extraabdominal desmoid tumor in a 19-year-old woman. (a, b) Sagittal T1-weighted (800/20) (a) and T2-weighted (2,000/100) (b) MR images show a heterogeneous intermuscular soft-tissue mass in the popliteal fossa (arrowheads). Bands of low signal intensity (white arrows in a, solid arrows in b) are prominent. Linear extension along fascial planes inferiorly (black arrows in a, open arrow in b) was not recognized at surgical resection. (c) Sagittal T1-weighted MR image (500/20) obtained 16 months after surgical resection shows a recurrent intermuscular soft-tissue mass (arrows) along the gastrocnemius muscle and soleus aponeurosis at the site of previously identified fascial extension. The mass has signal intensity characteristics similar to those of the original lesion, with bands of low signal intensity (arrowheads).
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Figure 15a. Radiation therapy of aggressive fibromatosis in an 18-year-old man. (a) Sagittal T2-weighted MR image (2,500/100) obtained before radiation therapy shows a large mass (arrowheads) involving the infraspinatus and subscapularis muscles. (b) Sagittal T2-weighted MR image (2,500/120) obtained 2 months later shows a decrease in both the size and signal intensity of the lesion (arrows). (c, d) Photomicrographs (original magnification, x200; hematoxylin-eosin stain) obtained before (c) and after (d) treatment show that decreased cellularity and increased fibrosis (pink material) from a good response to the radiation therapy are the cause of the imaging findings.
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Figure 15b. Radiation therapy of aggressive fibromatosis in an 18-year-old man. (a) Sagittal T2-weighted MR image (2,500/100) obtained before radiation therapy shows a large mass (arrowheads) involving the infraspinatus and subscapularis muscles. (b) Sagittal T2-weighted MR image (2,500/120) obtained 2 months later shows a decrease in both the size and signal intensity of the lesion (arrows). (c, d) Photomicrographs (original magnification, x200; hematoxylin-eosin stain) obtained before (c) and after (d) treatment show that decreased cellularity and increased fibrosis (pink material) from a good response to the radiation therapy are the cause of the imaging findings.
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Figure 15c. Radiation therapy of aggressive fibromatosis in an 18-year-old man. (a) Sagittal T2-weighted MR image (2,500/100) obtained before radiation therapy shows a large mass (arrowheads) involving the infraspinatus and subscapularis muscles. (b) Sagittal T2-weighted MR image (2,500/120) obtained 2 months later shows a decrease in both the size and signal intensity of the lesion (arrows). (c, d) Photomicrographs (original magnification, x200; hematoxylin-eosin stain) obtained before (c) and after (d) treatment show that decreased cellularity and increased fibrosis (pink material) from a good response to the radiation therapy are the cause of the imaging findings.
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Figure 15d. Radiation therapy of aggressive fibromatosis in an 18-year-old man. (a) Sagittal T2-weighted MR image (2,500/100) obtained before radiation therapy shows a large mass (arrowheads) involving the infraspinatus and subscapularis muscles. (b) Sagittal T2-weighted MR image (2,500/120) obtained 2 months later shows a decrease in both the size and signal intensity of the lesion (arrows). (c, d) Photomicrographs (original magnification, x200; hematoxylin-eosin stain) obtained before (c) and after (d) treatment show that decreased cellularity and increased fibrosis (pink material) from a good response to the radiation therapy are the cause of the imaging findings.
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Copyright © 2001 by the Radiological Society of North America.
