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DOI: 10.1148/rg.282075710
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RadioGraphics 2008;28:561-572
© RSNA, 2008


EDUCATION EXHIBIT

Imaging of Non–Small Cell Lung Cancer of the Superior Sulcus

Part 2: Initial Staging and Assessment of Resectability and Therapeutic Response1

John F. Bruzzi, FFRRCSI, Ritsuko Komaki, MD, Garrett L. Walsh, MD, Mylene T. Truong, MD, Gregory W. Gladish, MD, Reginald F. Munden, MD, and Jeremy J. Erasmus, MD

1 From the Division of Diagnostic Imaging (J.F.B., M.T.T., G.W.G., R.F.M., J.J.E.), Department of Radiation Oncology (R.K.), and Department of Thoracic and Cardiovascular Surgery (G.L.W.), M. D. Anderson Cancer Center, Houston, Tex. Received March 9; revision requested May 25 and received June 26; accepted June 29. All authors have no financial relationships to disclose. Address correspondence to J.F.B., Department of Radiology, University College Hospital Galway, Galway, Ireland (e-mail: John.Bruzzi{at}hse.ie).

Imaging plays a crucial role in the diagnosis and staging of superior sulcus tumors, assessment of their resectability, determination of the optimal approach to disease management, and evaluation of the response to therapy. Computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET)/CT contribute important and complementary information. Whereas CT is optimal for depicting bone erosion and for staging of intrathoracic disease, MR imaging is superior for evaluating tumor extension to the intervertebral neural foramina, the spinal cord, and the brachial plexus, primarily because of the higher contrast resolution and multiplanar capability available with MR imaging technology. Use of PET/CT enables the detection of unsuspected nodal and distant metastases. However, imaging has only limited usefulness for evaluating the response of a tumor to induction therapy and detecting local recurrence, and surgical biopsy often is necessary to verify the results of therapy.

© RSNA, 2008


Related Article

Imaging of Non–Small Cell Lung Cancer of the Superior Sulcus: Part 1: Anatomy, Clinical Manifestations, and Management
John F. Bruzzi, Ritsuko Komaki, Garrett L. Walsh, Mylene T. Truong, Gregory W. Gladish, Reginald F. Munden, and Jeremy J. Erasmus
RadioGraphics 2008 28: 551-560. [Abstract] [Full Text] [PDF]






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