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DOI: 10.1148/rg.27si075507
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RadioGraphics 2007;27:S197-S213
© RSNA, 2007

FDG PET/CT for the Detection and Evaluation of Breast Diseases: Usefulness and Limitations1

Hyo Soon Lim, MD, Woong Yoon, MD, Tae Woong Chung, MD, Jae Kyu Kim, MD, Jin Gyoon Park, MD, Heoung Keun Kang, MD, Hee Seung Bom, MD, and Jung Han Yoon, MD

1 From the Departments of Diagnostic Radiology (H.S.L., W.Y., T.W.C., J.K.K., J.G.P., H.K.K.), Nuclear Medicine (H.S.B.), and Surgery (J.H.Y.), Chonnam National University Medical School, Chonnam National University Hwasun Hospital, 160 Ilsimri, Hwasuneup, Hwasungun, Jeollanam-do 519-809, South Korea. Presented as an education exhibit at the 2006 RSNA Annual Meeting. Received February 20, 2007; revision requested March 20 and received April 9; accepted April 18. All authors have no financial relationships to disclose. Address correspondence to H.S.L. (e-mail: nico1220{at}dreamwiz.com).

Positron emission tomography (PET) with fluorine 18 fluorodeoxyglucose (FDG) is used to diagnose, stage, and monitor breast cancer. FDG PET has the capability to depict abnormal metabolic activity before any anatomic change occurs; however, in the absence of identifiable anatomic structures on PET images, it may be impossible to identify the location of areas of increased radionuclide uptake. In such cases, the coregistration of PET images with images from computed tomography (CT) may help improve diagnostic accuracy and lead to better clinical management of patients with breast cancer. Although FDG PET/CT may have limited diagnostic value for detecting small primary breast tumors, well-differentiated breast cancer, or regional lymph node involvement, it is superior to conventional imaging modalities for detecting distant metastases and recurrences and for monitoring the response to therapy.

© RSNA, 2007






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