HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) CME Test (opens in a new window) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Claus, F. G. Articles by Hattery, R. R. Search for Related Content PubMed PubMed Citation Articles by Claus, F. G. Articles by Hattery, R. R. Related Collections Genitourinary Radiology Magnetic Resonance Imaging

Pretreatment Evaluation of Prostate Cancer: Role of MR Imaging and ¹H MR Spectroscopy¹

¹ From the Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, C278, New York, NY 10021 (F.G.C., H.H.); and Department of Diagnostic Radiology, University of Arizona, Tucson (R.R.H.). Received March 30, 2004; revision requested April 19; revision received May 5 and accepted May 11. All authors have no financial relationships to disclose. Supported by National Institutes of Health grant R01 CA76423. Address correspondence to F.G.C. (e-mail: clausf@mskcc.org).

Magnetic resonance (MR) imaging and hydrogen 1 MR spectroscopy of the prostate gland are performed during the same examination with a conventional clinical MR unit. Prostate zonal anatomy and prostate cancer are best depicted on multiplanar T2-weighted MR images. MR imaging and ¹H MR spectroscopy are not used as an initial diagnostic tool. Their use in tumor detection is reserved for patients with elevated prostate-specific antigen levels in whom previous biopsy results were negative. The use of MR imaging and ¹H MR spectroscopy for the evaluation of tumor location, local extent (extracapsular extension and/or seminal vesicle invasion), volume, and aggressiveness is generating strong clinical interest. In staging and treatment planning, MR imaging has been shown to have an incremental value additive to the value of clinical nomograms. Furthermore, anatomic and metabolic mapping of the prostate gland with ¹H MR spectroscopy offers the possibility of optimizing treatment planning (watchful waiting, surgery, or radiation therapy [intensity-modulated radiation therapy or brachytherapy]), thus further expanding the role of MR imaging in the achievement of patient-specific, individualized treatment.

© RSNA, 2004

Index Terms: Neoplasms, staging, 844.1214, 844.12145 • Prostate neoplasms, MR, 844.1214, 844.12145

This article has been cited by other articles:

				C. K. Kuhl, F. Traber, J. Gieseke, W. Drahanowsky, N. Morakkabati-Spitz, W. Willinek, M. von Falkenhausen, C. Manka, and H. H. Schild Whole-Body High-Field-Strength (3.0-T) MR Imaging in Clinical Practice * Part II. Technical Considerations and Clinical Applications Radiology, April 1, 2008; 247(1): 16 - 35. [Abstract] [Full Text] [PDF]

				S. W. T. P. J. Heijmink, J. J. Futterer, T. Hambrock, S. Takahashi, T. W. J. Scheenen, H. J. Huisman, C. A. Hulsbergen-Van de Kaa, B. C. Knipscheer, L. A. L. M. Kiemeney, J. A. Witjes, et al. Prostate Cancer: Body-Array versus Endorectal Coil MR Imaging at 3 T--Comparison of Image Quality, Localization, and Staging Performance Radiology, July 1, 2007; 244(1): 184 - 195. [Abstract] [Full Text] [PDF]

				H. Hricak, P. L. Choyke, S. C. Eberhardt, S. A. Leibel, and P. T. Scardino Imaging Prostate Cancer: A Multidisciplinary Perspective Radiology, April 1, 2007; 243(1): 28 - 53. [Abstract] [Full Text] [PDF]

				L. Wang, J. Zhang, L. H. Schwartz, H. Eisenberg, N. M. Ishill, C. S. Moskowitz, P. Scardino, and H. Hricak Incremental Value of Multiplanar Cross-Referencing for Prostate Cancer Staging with Endorectal MRI Am. J. Roentgenol., January 1, 2007; 188(1): 99 - 104. [Abstract] [Full Text] [PDF]

				Y. J. Choi, J. K. Kim, N. Kim, K. W. Kim, E. K. Choi, and K.-S. Cho Functional MR Imaging of Prostate Cancer RadioGraphics, January 1, 2007; 27(1): 63 - 75. [Abstract] [Full Text] [PDF]

				O. Akin, E. Sala, C. S. Moskowitz, K. Kuroiwa, N. M. Ishill, D. Pucar, P. T. Scardino, and H. Hricak Transition Zone Prostate Cancers: Features, Detection, Localization, and Staging at Endorectal MR Imaging Radiology, June 1, 2006; 239(3): 784 - 792. [Abstract] [Full Text] [PDF]

				E. Sala, O. Akin, C. S. Moskowitz, H. F. Eisenberg, K. Kuroiwa, N. M. Ishill, B. Rajashanker, P. T. Scardino, and H. Hricak Endorectal MR Imaging in the Evaluation of Seminal Vesicle Invasion: Diagnostic Accuracy and Multivariate Feature Analysis Radiology, March 1, 2006; 238(3): 929 - 937. [Abstract] [Full Text] [PDF]

				E. Sala, S. C. Eberhardt, O. Akin, C. S. Moskowitz, C. N. Onyebuchi, K. Kuroiwa, N. Ishill, M. J. Zelefsky, J. A. Eastham, and H. Hricak Endorectal MR Imaging before Salvage Prostatectomy: Tumor Localization and Staging Radiology, January 1, 2006; 238(1): 176 - 183. [Abstract] [Full Text] [PDF]

				L. Wang, H. Hricak, M. W. Kattan, H.-N. Chen, P. T. Scardino, and K. Kuroiwa Prediction of Organ-confined Prostate Cancer: Incremental Value of MR Imaging and MR Spectroscopic Imaging to Staging Nomograms Radiology, December 12, 2005; (2005) 2382041905. [Abstract] [Full Text]