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Thoracic Manifestations of Behçet Disease at CT¹

¹ From the Department of Radiology, Hadassah University Hospital, Ein-Kerem, Jerusalem, Israel 91120 (N.H., S.L., J.B.Z., D.S.); and the Department of Internal Medicine, Hadassah Mount Scopus University Hospital, Jerusalem, Israel (T.C.S.). Presented as an education exhibit at the 2002 RSNA scientific assembly. Received April 1, 2003; revision requested May 16 and received June 27; accepted June 27. All authors have no financial relationships to disclose. Address correspondence to D.S. (e-mail: dshaham@hadassah.org.il).

Behçet disease is a multisystemic and chronic inflammatory disorder of unknown cause that is characterized by recurrent oral and genital ulcerations, ocular manifestations, and additional clinical manifestations in multiple organ systems. Behçet disease involving the chest can manifest as a wide spectrum of abnormalities. Although conventional chest radiography is commonly used for initial assessment, spiral computed tomography can demonstrate the entire spectrum of thoracic manifestations of Behçet disease, including abnormalities of the vessel lumen and wall, perivascular tissues, lung parenchyma, pleura, and mediastinal structures. Aneurysms of the pulmonary arteries, with or without thrombosis, are a typical manifestation of Behçet disease. Other manifestations include thrombosis, vasculitis, hemorrhage, infarction, and inflammation. Familiarity with these manifestations can be useful in the diagnosis of Behçet disease, helping to determine the cause of symptoms in patients who present with hemoptysis and guide the choice of appropriate therapy.

© RSNA, 2004

Index Terms: Behçet disease, 92.629, 94.629 • Lung, diseases, 60.629 • Pulmonary arteries, diseases, 944.629 • Pulmonary arteries, thrombosis, 944.751 • Thorax, CT, 94.1211 • Thorax, diseases, 94.629

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