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Special Focus Session

What’s New in Cartilage?¹

¹ From the Department of Radiology, Stanford University, Packard EE Bldg, Rm 222, Stanford, CA 94305-9510 (G.E.G.); the Department of Radiology, Yale University, New Haven, Conn (T.R.M.); the Division of Health Sciences and Technology, Harvard University–Massachusetts Institute of Technology, Cambridge, Mass (M.L.G.); and Commonwealth Radiology, Richmond, Va (D.G.D.). From the Plenary Session, Special Focus Session: What’s New in Cartilage? presented at the 2002 RSNA scientific assembly. Received April 17, 2003; revision requested April 23 and received May 21; accepted May 27. Supported by grants AR46904-02 and AR41773-04 from the National Institutes of Health, by the Whitaker Foundation, and by the Arthritis Foundation. Address correspondence to G.E.G. (e-mail: gold@stanford.edu).

Magnetic resonance (MR) imaging of articular cartilage is important in evaluation of new surgical and pharmacologic treatments for cartilage damage. Many techniques exist for MR imaging of articular cartilage. Standard techniques for morphologic imaging of cartilage include fast spin-echo and spoiled gradient-echo imaging. These methods provide high-resolution morphologic images of cartilage but are time-consuming in the clinical setting. New methods for faster or higher-resolution morphologic imaging include techniques based on steady-state free precession imaging. These fast techniques will allow detailed evaluation of cartilage in the routine clinical setting. There are also several MR imaging methods that may provide information about the structure and physiology of cartilage. Physiologic imaging may allow detailed evaluation of the glycosaminoglycan matrix or collagen network of articular cartilage and may be the most sensitive method for detection of early changes. With the development of new therapies for osteoarthritis and cartilage injury, MR imaging of articular cartilage is of increasing clinical importance. MR imaging will play an important role in evaluation of the effectiveness of these therapies.

© RSNA, 2003

Index Terms: Cartilage, MR, 4521.1214 • Joints, MR, 40.1214 • Knee, ligaments, menisci, and cartilage, 4521.4851, 4521.77 • Knee, MR, 4521.1214

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