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SCIENTIFIC EXHIBIT |
1 From the Department of Radiology, Ohio State University Medical Center, S-209 Rhodes Hall, 450 W 10th Ave, Columbus, OH 43210 (K.M.V.); the Department of Radiology, Beth Israel Deaconess Medical Center, Boston, Mass (M.T.K.); and the Department of Radiology, Duke University Medical Center, Durham, NC (C.E.S., R.C.N.). Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received April 21, 1999; revision requested May 12 and received July 13; accepted July 14. Address correspondence to K.M.V.
Magnetic resonance cholangiopancreatography (MRCP) is used for noninvasive work-up of patients with pancreaticobiliary disease. MRCP is comparable with invasive endoscopic retrograde cholangiopancreatography (ERCP) for diagnosis of extrahepatic bile duct abnormalities. In patients with choledocholithiasis, calculi appear as dark filling defects within the high-signal-intensity fluid at MRCP. Benign strictures due to sclerosing cholangitis are multifocal and alternate with slight dilatation or normal-caliber bile ducts, producing a beaded appearance. Dilatation of both the pancreatic and bile ducts at MRCP is highly suggestive of a pancreatic head malignancy. Side-branch ectasia is the most prominent and specific feature of chronic pancreatitis. MRCP is more sensitive than ERCP in detection of pancreatic pseudocysts because less than 50% of pseudocysts fill with contrast material. Because the mucin secreted by biliary cystadenomas and cystadenocarcinomas causes filling defects and partial obstruction of contrast material at ERCP, MRCP is potentially more accurate in demonstrating the extent of these tumors. In patients with biliary-enteric anastomoses, MRCP is the imaging modality of choice for the work-up of suspected pancreaticobiliary disease. A potential use of MRCP is the demonstration of aberrant bile duct anatomy before cholecystectomy. MRCP is also accurate in detection of pancreas divisum.
Index Terms: Bile ducts, abnormalities, 76.1497 Bile ducts, calculi, 766.289 Bile ducts, neoplasms, 76.30 Bile ducts, stenosis or obstruction, 76.2886 Bile ducts, surgery, 76.453 Magnetic resonance (MR), cholangiopancreatography, 76.12149 Pancreas, cysts, 770.3123 Pancreatic ducts, 774.1491 Pancreatitis, 770.291
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