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(Radiographics. 2000;20:1007-1019.)
© RSNA, 2000


SCIENTIFIC EXHIBIT

Myxoid Liposarcoma: Appearance at MR Imaging with Histologic Correlation1

Mi-Sook Sung, MD, Heong S. Kang, MD, Jin S. Suh, MD, Jung H. Lee, MD, Jeong M. Park, MD, Jee Y. Kim, MD and Hae G. Lee, MD

1 From the Department of Radiology, Catholic University of Korea at Holy Family Hospital, Sosa-dong, Puchun, Kyunggido 420-717, Korea (M.S.S., J.M.P., J.Y.K., H.G.L.); the Department of Radiology, Seoul National University Hospital, Seoul, Korea (H.S.K.); the Department of Radiology, Yonsei University, Shinchon Severance Hospital, Seoul (J.S.S.); and the Department of Radiology, Korea Cancer Center, Seoul (J.H.L.). Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received April 8, 1999; revision requested May 6 and received July 2; accepted July 7. Address correspondence to M.S.S. (e-mail: mssung@clin.hfh.cuk.ac.kr).

Although myxoid liposarcoma is a subtype of liposarcoma, it may be difficult to establish the correct diagnosis with magnetic resonance (MR) imaging due to the lack of fat signal intensity. Without the administration of gadolinium contrast material, the tumor may even mimic a cystic tumor. A spectrum of MR imaging abnormalities occur in myxoid liposarcoma, depending on the amount of fat and myxoid material, the degree of cellularity and vascularity, and the presence of necrosis. Most myxoid liposarcomas have lacy or linear, amorphous foci of fat. Some myxoid liposarcomas appear to be cystic at nonenhanced MR imaging, although they enhance like other solid masses at contrast material–enhanced MR imaging. The enhancing areas within the tumor represent increased cellularity and vascularity; the nonenhancing areas represent necrosis, reduced cellularity, and accumulated mucinous material. Gadolinium-enhanced imaging is important in differentiating myxoid liposarcoma from benign cystic tumors. Characterization of the tumor with MR imaging plays an important role in the management of myxoid liposarcoma.

Index Terms: Liposarcoma, 40.371 • Soft tissues, MR, 40.121411 • Soft tissues, neoplasms, 40.371 • Soft tissues, US, 40.12981




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