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SCIENTIFIC EXHIBIT |
1 From the Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap Dong Songpa-Ku, Seoul 138-040, Korea (H.K.H., S.H.L., S.E.R., J.H.K., J.G.K., P.N.K., M.G.K., Y.H.A.); the Department of Radiology, Kangnam St Mary Hospital, Catholic University College of Medicine, Seoul, Korea (J.Y.B.); the Department of Radiology, Samg Sung Medical Center College of Medicine, Sung Kyun Kwan University, Seoul, Korea (H.K.L.); and the Department of Radiology, Seoul National University College of Medicine, Seoul, Korea (J.W.C.). Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received February 22, 1999; revision requested April 19 and final revision received July 6; accepted July 7. Address reprint requests to H.K.H. (e-mail: hkha@www.amc.seoul.kr).
Vasculitides can cause local or diffuse pathologic changes in the gastrointestinal tract, resulting in nonspecific paralytic ileus, mesenteric ischemia, submucosal edema and hemorrhage, or bowel perforation or stricture. The extent and clinical course of disease depend on the size and location of the affected vessel and the histologic characteristics of the lesion. Vasculitis may primarily involve large vessels (eg, giant cell arteritis, Takayasu arteritis), medium-sized vessels (eg, polyarteritis nodosa, Kawasaki disease, primary granulomatous central nervous system vasculitis), or small vessels (eg, Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, Henoch-Schönlein syndrome, systemic lupus erythematosus, rheumatoid vasculitis, Behçet syndrome). Radiologic findings in various types of vasculitis often overlap considerably and therefore have limited value in making a specific diagnosis. Nevertheless, the possibility of vasculitis should be considered whenever mesenteric ischemic changes occur in young patients, are noted at unusual sites (eg, stomach, duodenum, rectum), have a tendency to concomitantly involve the small and large intestine, and are associated with genitourinary involvement. Knowledge of systemic clinical manifestations in affected patients may suggest and even help establish the specific diagnosis.
Index Terms: Behçet disease, 70.629 Gastrointestinal tract, angiography, 70.124 Gastrointestinal tract, CT, 70.1211 Gastrointestinal tract, inflammation, 70.62 Gastrointestinal tract, vasculitis, 70.62 Lupus erythematosus, 70.612 Vasculitis, 70.62
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