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(Radiographics. 2000;20:449-470.)
© RSNA, 2000

SCIENTIFIC EXHIBIT

Tuberculosis from Head to Toe1

(CME available in print version and on RSNA Link)

Mukesh G. Harisinghani, MD , Theresa C. McLoud, MD, Jo-Anne O. Shepard, MD, Jane P. Ko, MD, Manohar M. Shroff, MD and Peter R. Mueller, MD

1 From the Department of Radiology, Ellison 234, Massachusetts General Hospital, Harvard Medical School, 32 Fruit St, Boston, MA 02114 (M.G.H., T.C.M., J.O.S., J.P.K., P.R.M.), and the Department of Radiology, P.D. Hinduja National Hospital, Mahim, Bombay, India (M.M.S.). Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received February 19, 1999; revision requested April 14 and received June 18; accepted June 21. Address reprint requests to M.G.H. (e-mail: mharisinghani@partners.org).

Tuberculosis can affect virtually any organ system in the body and can be devastating if left untreated. The increasing prevalence of tuberculosis in both immunocompetent and immunocompromised individuals in recent years makes this disease a topic of universal concern. Because tuberculosis demonstrates a variety of clinical and radiologic findings and has a known propensity for dissemination from its primary site, it can mimic numerous other disease entities. Primary pulmonary tuberculosis typically manifests radiologically as parenchymal disease, lymphadenopathy, pleural effusion, miliary disease, or lobar or segmental atelectasis. In postprimary tuberculosis, the earliest radiologic finding is the development of patchy, ill-defined segmental consolidation. Both computed tomography (CT) and magnetic resonance (MR) imaging are helpful in diagnosing tuberculous spondylitis and tuberculous arthritis. CT is especially useful in depicting gastrointestinal and genitourinary tuberculosis. In tuberculosis involving the central nervous system, CT and MR imaging findings vary depending on the stage of disease and the character of the lesion. A high degree of clinical suspicion and familiarity with the various radiologic manifestations of tuberculosis allow early diagnosis and timely initiation of appropriate therapy, thereby reducing patient morbidity.

Index Terms: Tuberculosis, central nervous system, 10.236, 30.236, 139.23, 139.251 • Tuberculosis, gastrointestinal, 70.23 • Tuberculosis, genitourinary, 80.23 • Tuberculosis, musculoskeletal, 30.231, 40.23 • Tuberculosis, pulmonary, 60.231, 60.232




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