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SCIENTIFIC EXHIBIT |
1 From the Department of Radiology (J.A.S., J.E.L., F.M.) and the Department of Medicine, Division of Gastroenterology (O.A., J.C.R., G.C.), Universidad de Antioquia, Hospital Universitario San Vicente de Paúl, Calle 64 x Carrera 51D, Medellín, Colombia. Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received March 1, 1999; revision requested April 21 and received May 12; accepted May 14. Address reprint requests to J.A.S. (e-mail: jorgeasoto@aol.com).
Twenty-two patients with malignant biliary obstruction and 21 patients with suspected obstruction of biliary-enteric anastomoses were evaluated over a 12-month period with magnetic resonance (MR) cholangiography and cross-sectional MR imaging. In patients with malignant obstruction, MR cholangiography helped accurately determine the status of the biliary ductal system by identifying the exact location and extent of the obstruction and the severity of duct dilatation. In so doing, MR cholangiography helped determine whether percutaneous transhepatic cholangiography with antegrade stent placement or retrograde cholangiography with stent placement constituted the more suitable treatment. Cross-sectional MR imaging was necessary to identify the organ of tumor origin, define the tumor margins, and determine the stage of disease. This information helped evaluate the appropriateness of curative surgical therapy versus palliative drainage procedures. In patients with biliary-enteric anastomoses, MR cholangiography clearly depicted the site of the anastomosis and demonstrated the status of the intrahepatic ducts, thereby helping determine which patients would benefit from undergoing antegrade duct cannulation with a drainage procedure or perhaps balloon dilation. In some of these patients, MR cholangiography was sufficient to help plan therapeutic intervention. MR cholangiography also demonstrates the presence and size of biliary stones and associated findings such as intraductal tumor growth. In addition, MR cholangiography may obviate retrograde cholangiography, which can be technically difficult to perform.
Index Terms: Bile duct radiography, 76.122 Bile ducts, calculi, 76.28 Bile ducts, MR, 76.121411, 121412, 121415 Bile ducts, stenosis or obstruction, 76.28 Bile ducts, surgery, 76.453
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