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(Radiographics. 1999;19:1465-1485.)
© RSNA, 1999


SCIENTIFIC EXHIBIT

A Pattern-oriented Approach to Splenic Imaging in Infants and Children1

Anne Paterson, MRCP, FRCR , Donald P. Frush, MD , Lane F. Donnelly, MD , Joseph N. Foss, MD , Sara M. O'Hara, MD and George S. Bisset, III, MD

1 From the Department of Radiology, Division of Pediatric Radiology, Duke University Medical Center, Durham, NC 27710. Presented as a scientific exhibit at the 1998 RSNA scientific assembly. Received February 16, 1999; revision requested March 16 and received April 1; accepted April 1. Address reprint requests to D.P.F.

The spleen in infants and children is commonly involved in a variety of pathologic processes. Some of these processes cause isolated splenic disease, whereas others involve the spleen as part of a systemic illness. To facilitate differential diagnosis of splenic abnormalities, a pattern-oriented approach to the imaging evaluation of the pediatric spleen was developed. With this approach, splenic anomalies are categorized as anomalies of splenic shape (clefts, notches, lobules), location (eg, wandering spleen), number (polysplenia, asplenia), or size (splenomegaly, splenic atrophy); solitary lesions (eg, cysts, lymphangiomas, hemangiomas, hamartomas); multiple focal lesions (eg, trauma, infection and inflammation, neoplasms, storage disorders); and diffuse disease without focal lesions (eg, infarction, heavy metal deposition, hemangioendotheliomas, peliosis). A variety of imaging modalities can be used in splenic assessment, including computed tomography, magnetic resonance imaging, ultrasound, and technetium-99m scintigraphy. The imaging appearance of the pediatric spleen depends on the patient's age and the modality used; however, familiarity with the spectrum of radiologic patterns of splenic involvement will facilitate correct diagnosis and prompt treatment.

Index Terms: Children, gastrointestinal system, 775.**2 • Infants, gastrointestinal system, 775.**2 • Spleen, abnormalities, 775.134, 775.1653 • Spleen, CT, 775.12112 • Spleen, MR, 775.12141 • Spleen, radionuclide studies, 775.12171 • Spleen, size, 775.372 • Spleen, US, 775.1298




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