Figure 3b. Endophytic retinoblastoma in a 2-year-old girl with a white pupillary reflex in the right eye. (a) Photograph (hematoxylin-eosin [H-E] stain) of the whole-mount specimen shows a mass growing from the medial retina (arrowhead) toward the vitreous posterior to the lens (curved arrow). Calcifications are seen in the tumor (straight arrow). The tumor does not involve the optic nerve (*). (b) Unenhanced CT image shows the densely calcified mass abutting the retina in the medial right globe.