Figure 10a. Biopsy-proved adenocarcinoma in the central zone in both lobes of the prostate in a 67-year-old man. (a) Axial T2-weighted MR image shows areas of abnormally low signal intensity (arrow), a finding that is not definitively indicative of cancer. (b, c) MR spectrum (b) and spectroscopic image (c) show high ratios (in arbitrary units) of choline (Ch) and creatine (Cr) to citrate (Ci) in three areas (arrows in c). The findings were indicative of cancer, which was diagnosed at targeted biopsy.