Figure 8c. Tamoxifen-induced adenomyoma in a 56-year-old woman. The patient underwent breast-conserving therapy for breast carcinoma 2 years earlier and was treated with tamoxifen. (a) Sagittal T2-weighted image shows a polypoid mass of heterogeneous high signal intensity in the endometrial cavity (arrows). (b) Sagittal contrast-enhanced T1-weighted image shows that the mass (arrows) enhances as well as the myometrium. (c) Photomicrograph (original magnification, x20; H-E stain) shows endometrial tissue surrounded by hyperplastic smooth muscle.