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Figure 5a.  Noguchi type D adenocarcinoma (poorly differentiated adenocarcinoma) in a 62-year-old woman. (a) Transaxial thin-section (1-mm collimation) CT scan (lung window) obtained at the level of the left main bronchus shows a 21-mm nodule with a spiculated margin in the left upper lobe. (b) Low-power photomicrograph (original magnification, x12; H-E stain) of a surgical specimen shows a poorly differentiated solid adenocarcinoma with a well-defined margin (arrows). The surgical specimens showed no hilar or mediastinal nodal metastasis, and no recurrence was seen at postoperative follow-up.