Figure 2c. Small adenoma in a 51-year-old woman. (a) Axial in-phase FMPSPGR T1-weighted MR image (150/4.2, flip angle = 90°) shows an ovoid mass that arises from the medial limb of the left adrenal gland (arrow). A large hemangioma (*) was seen incidentally in the liver (L). (b) Axial out-of-phase FMPSPGR T1-weighted MR image (150/1.8, flip angle = 90°) shows no signal dropout in the mass (arrow). This finding is uncharacteristic of adenomas, which classically show signal dropout with the out-of-phase sequence. L = liver, * = hemangioma. (c) Photomicrograph (original magnification, x400; H-E stain) shows a lipid-poor adrenal adenoma that contains predominantly eosinophilic compact cells with abundant lipofuscin pigment, which appears brown (arrow). These histologic findings may account for the lack of signal dropout in b.