Figure 3a. Cavernous angioma. (a) Axial T2-weighted MR image of the brain shows a left frontal periventricular nodular lesion with a thick hypointense rim (arrow). (b) High-power photomicrograph (original magnification, x400; hematoxylin-eosin [H-E] stain) shows multiple vascular spaces of varying size. The vessels are stacked on top of each other with no intervening brain tissue.