Figure 3. Desmoplastic-nodular medulloblastoma. Photomicrograph (original magnification x400; hematoxylin-eosin stain) of a desmoplastic-nodular medulloblastoma shows a prominent nodule, or "pale island," (I) containing small, uniform neurocytic cells with abundant cytoplasm. Smaller pale islands surround the dominant nodule. The internodular zones often contain abundant reticulin and are populated by more atypical cells.