Figure 18c. Malignant lymphoma in a 48-year-old woman with multiple swollen lymph nodes in the paraaortic and supraclavicular regions. (a) Sagittal T1-weighted image shows extensive uniform enlargement of the uterus (arrowheads), which has homogeneous low signal intensity. (b) Sagittal T2-weighted image shows diffuse symmetrical enlargement of the uterus, especially of the cervix (arrows). The lack of signal in the cervical stroma is obvious. The myometrium also lacks its zonal appearance and has low signal intensity with an irregular contour. The cause of this signal intensity is unknown. (c) Sagittal contrast-enhanced T1-weighted image shows heterogeneous enhancement of the uterus. The diagnosis of malignant lymphoma was established by means of biopsy of a lymph node. The uterine lesion significantly decreased in size with chemotherapy and was considered to represent uterine involvement by lymphoma.