Figure 1a. Lateral (a) and anteroposterior (b) radiographs of the leg in a 35-year-old man. The marrow abnormality is barely discernible as a permeative pattern. The more prominent, but still subtle, abnormality is the endosteal thickening of the cortex, seen posteriorly on the lateral view and medially on the anteroposterior view. Results of biopsy of the marrow showed primary lymphoma of bone.