Figure 13c. MR imaging appearance. (a) Frontal radiograph of the right knee in a 31-year-old man with a history of knee injuries reveals a mixed lytic and sclerotic lesion in the distal femur. (b) Coronal T1-weighted image (600/15) shows the predominantly intramedullary lesion with minimal cortical erosion. (c) Axial T2-weighted image (2,500/80) also shows the intramedullary component, as well as a small joint effusion. Analysis of the biopsy specimen revealed primary Hodgkin lymphoma of the bone.