Figure 21. Normal pancreas (A, B) and chronic pancreatitis (C, D) demonstrated with an axial GRE T1-weighted sequence with a water-stimulation prepulse. As with fat-suppression sequences, spectral water stimulation suppresses the fat signal and normal pancreas has high intensity. In chronic pancreatitis, the signal is dramatically reduced (*) because of the diffuse fibrosis in the gland.