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Figure 5c.   Ganglioglioma in a 20-year-old woman with an 8-year history of partial complex seizures. (a) Coronal T1-weighted MR image shows a focal hypointense mass (arrow) of the medial left temporal lobe. (b) Coronal T2-weighted MR image shows high signal intensity within the mass without evidence of surrounding edema. (c) Contrast-enhanced coronal T1-weighted MR image shows intense focal enhancement (arrowheads) of the medial margin of the mass extending to the cortical surface. (d) Photograph of a specimen obtained after en bloc resection of the lateral temporal cortex shows abnormal enlargement of the gyrus. Histologic examination of this specimen showed abnormal ganglion cells combined with abnormal astrocytes and oligodendrocytes, which confirmed the diagnosis.