Figure 14a. Case 4. (a) Photomicrograph (original magnification, x60; H-E stain) of a specimen taken from the wall of a cystic mass from a different patient reveals thyroid tissue. Small histologic rests of thyroid tissue embedded in the cystic wall are a normal finding in a thyroglossal duct cyst, which arises from persistent anlage of the thyroid gland. (b) Photomicrograph (original magnification, x150; H-E stain) of another specimen from the wall of the thyroglossal duct cyst shows the typical papillary appearance of papillary thyroid adenocarcinoma.