Figure 3. Figures 1–3 (1) Gleason grade 2 adenocarcinoma. Photomicrograph shows a tumor composed of well-formed round glands growing in a relatively circumscribed nodule. (2) Gleason grade 3 adenocarcinoma. Photomicrograph shows a tumor composed of uniform small glands that are growing in an infiltrative pattern. (3) Gleason grade 4 adenocarcinoma. Photomicrograph of a needle biopsy specimen shows the tumor growing as solid fused glands. A benign gland is seen in the center.